TY  - JOUR
TI  - Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys
AU  - Ronald C. Kessler
AU  - Katie A. McLaughlin
AU  - Jennifer Green
AU  - Michael J. Gruber
AU  - Nancy A. Sampson
AU  - Alan M. Zaslavsky
AU  - Sergio Aguilar‐Gaxiola
AU  - Ali Al-Hamzawi
AU  - Jordi Alonso
AU  - Matthias C. Angermeyer
AU  - Corina Benjet
AU  - Evelyn J. Bromet
AU  - Somnath Chatterji
AU  - Giovanni de Girolamo
AU  - Koen Demyttenaere
AU  - John Fayyad
AU  - Silvia Florescu
AU  - Gilad Gal
AU  - Oye Gureje
AU  - Josep María Haro
AU  - Chiyi Hu
AU  - Elie G. Karam
AU  - Norito Kawakami
AU  - Sing Lee
AU  - Jean‐Pierre Lépine
AU  - Johan Ormel
AU  - José Posada‐Villa
AU  - Rajesh Sagar
AU  - Adley Tsang
AU  - T. B. Üstün
AU  - Svetlozar Vassilev
AU  - María Carmen Viana
AU  - David R. Williams
PY  - 2010
JO  - The British Journal of Psychiatry
DO  - 10.1192/bjp.bp.110.080499
UR  - https://doi.org/10.1192/bjp.bp.110.080499
AB  - BACKGROUND: Although significant associations of childhood adversities with adult mental disorders are widely documented, most studies focus on single childhood adversities predicting single disorders. AIMS: To examine joint associations of 12 childhood adversities with first onset of 20 DSM-IV disorders in World Mental Health (WMH) Surveys in 21 countries. METHOD: Nationally or regionally representative surveys of 51 945 adults assessed childhood adversities and lifetime DSM-IV disorders with the WHO Composite International Diagnostic Interview (CIDI). RESULTS: Childhood adversities were highly prevalent and interrelated. Childhood adversities associated with maladaptive family functioning (e.g. parental mental illness, child abuse, neglect) were the strongest predictors of disorders. Co-occurring childhood adversities associated with maladaptive family functioning had significant subadditive predictive associations and little specificity across disorders. Childhood adversities account for 29.8% of all disorders across countries. CONCLUSIONS: Childhood adversities have strong associations with all classes of disorders at all life-course stages in all groups of WMH countries. Long-term associations imply the existence of as-yet undetermined mediators.
ER  -